Biosynthesis of Deoxyamphotericins and Deoxyamphoteronolides by Engineered Strains of Streptomyces nodosus

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway

Trygve Brautaset, Olga N. Sekurova, Håvard Sletta et al. · Chemistry & Biology · 2000 · 290 citations · Full text

Life Sciences, Microbiology, Molecular Biology +15

Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

Patrick Caffrey, Susan V. Lynch, Elizabeth M. Flood et al. · Chemistry & Biology · 2001 · 264 citations · Full text

Life Sciences, Biochemistry, Microbiology +14

Quantitative structure-activity relationships in amphotericin B derivatives

Monique Chéron, Barbara Cybulska, Jan Mazerski et al. · Biochemical Pharmacology · 1988 · 137 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Engineered biosynthesis of novel polyenes: a pimaricin derivative produced by targeted gene disruption in Streptomyces natalensis

Marta V. Mendes, Eliseo Recio, Roberto Fouces et al. · Chemistry & Biology · 2001 · 94 citations · Full text

Life Sciences, Biotechnology, Biochemical Engineering +16

The Molecular Basis of Celmer's Rules:  The Stereochemistry of the Condensation Step in Chain Extension on the Erythromycin Polyketide Synthase

Kira J. Weissman, M C Timoney, Peter Grice et al. · Biochemistry · 1997 · 94 citations

Pharmacy, Biochemistry, Chemistry +15