Short-chain fatty acids alter tight junction permeability in intestinal monolayer cells via lipoxygenase activation

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

Minoru Yoshida, Masako Kijima, Motomu Akita et al. · Journal of Biological Chemistry · 1990 · 1.9K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

The Effects of Short-Chain Fatty Acids on Human Colon Cancer Cell Phenotype Are Associated with Histone Hyperacetylation

Brian F. Hinnebusch, Shufen Meng, James T. Wu et al. · Journal of Nutrition · 2002 · 541 citations

Life Sciences, Biochemistry, Oncology +14

Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.

Ari Ristimäki, Susan Garfinkel, J Wessendorf et al. · Journal of Biological Chemistry · 1994 · 475 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Butyrate Activates the WAF1/Cip1 Gene Promoter through Sp1 Sites in a p53-negative Human Colon Cancer Cell Line

Katsunori Nakano, Takakazu Mizuno, Yoshihiro Sowa et al. · Journal of Biological Chemistry · 1997 · 396 citations · Full text

Medicine, Molecular Biology, Oncology +11

Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer.

John M. Mariadason, Georgia Corner, Leonard H. Augenlicht · PubMed · 2000 · 375 citations

Life Sciences, Genetics, Pharmacology +17