Vitamin D₃ Induces <scp>IDO</scp>⁺ Tolerogenic <scp>DC</scp>s and Enhances Treg, Reducing the Severity of <scp>EAE</scp>

Abstract

These mechanisms contribute actively to the generation of a microenvironment in the lymph nodes that suppresses the activation of encephalitogenic T cells, resulting in the downregulation of the inflammatory response in the central nervous system.