Matrix Metalloproteinase 2 Is Associated With Stable and Matrix Metalloproteinases 8 and 9 With Vulnerable Carotid Atherosclerotic Lesions

Joost P. G. Sluijter, Wilco P. Pulskens, Arjan H. Schoneveld, Evelyn Velema, Chaylendra Strijder, Frans L. Moll, Jean-Paul de Vries, Jan H. Verheijen, Roeland Hanemaaijer, Dominique P.V. de Kleijn,

Stroke · 2005 · 196 citations · 8 references

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Abstract

MMP-2, MMP-8, and MMP-9 activities differed among carotid plaque phenotypes. Different EMMPRIN glycosylation forms are associated with either MMP-2 or MMP-9 activity, which suggests that EMMPRIN glycosylation may play a role in MMP regulation and plaque destabilization.

References

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