Concepedia

Clinical characteristics of cytomegalovirus infection in rheumatic diseases: multicentre survey in a large patient population

Yasunobu Takizawa, Shigeko Inokuma, Yuji Tanaka, Kazuyoshi Saito, Tatsuya Atsumi, M. Hirakata, Hideto Kameda, Shunsei Hirohata, Hirofumi Kondo, Shunichi Kumagai,

Lara D. Veeken · 2008 · 147 citations · 24 references

DOIFull text

Open access

Abstract

CMV infection was mostly diagnosed by antigenaemia, and occurred among patients under strong immunosuppressive therapy using pulsed MPSL and/or immunosuppressants. Lymphopenia, presence of symptoms and other infections are significant risk factors for a poor outcome and pulsed MPSL and an older age may predict it. Patients were prone to be symptomatic with anti-genaemia count over 5.6/10(5) PMNs.

References

24

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

Nathalie Auphan‐Anezin, Joseph A. DiDonato, Caridad Rosette et al. · Science · 1995 · 2.4K citations

Transplantation Proceedings

Surgery · 2006 · 1.7K citations

A Randomized, Controlled Trial of Prophylactic Ganciclovir for Cytomegalovirus Pulmonary Infection in Recipients of Allogeneic Bone Marrow Transplants

G. Schmidt, David Hořák, Joyce C. Niland et al. · New England Journal of Medicine · 1991 · 625 citations · Full text

HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies

Mark Connors, Joseph A. Kovacs, Seth Krevat et al. · Nature Medicine · 1997 · 524 citations

, , +12

Monitoring of Human Cytomegalovirus Infections and Ganciclovir Treatment in Heart Transplant Recipients by Determination of Viremia, Antigenemia, and DNAemia

Giuseppe Gerna, Donato Zipeto, M. Parea et al. · The Journal of Infectious Diseases · 1991 · 297 citations

, , +13