Therapeutic effects of a reducible poly (oligo-d-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

Leo E. Otterbein, Fritz H. Bach, Jawed Alam et al. · Nature Medicine · 2000 · 2.1K citations

Inflammation, Anti-inflammatory, Signal Transduction +15

HMGB1, a Novel Cytokine-Like Mediator Linking Acute Neuronal Death and Delayed Neuroinflammation in the Postischemic Brain

J.-B. Kim, Jiwon Choi, Young‐Mi Yu et al. · Journal of Neuroscience · 2006 · 570 citations · Full text

Hmgb1 Shrna Expression, Immunology, Cell Death +18

Haem oxygenase-1 prevents cell death by regulating cellular iron

Christopher D. Ferris, Samie R. Jaffrey, Akira Sawa et al. · Nature Cell Biology · 1999 · 510 citations

Biochemistry, Heme Homeostasis, Heme Degradation +9

Role of IL-1alpha and IL-1beta in ischemic brain damage.

Hervé Boutin, R.A. LeFeuvre, Reiko Horai et al. · PubMed · 2001 · 480 citations · Full text

Immunology, Cerebral Vascular Regulation, Neuroinflammation +18

Role of IL-1α and IL-1β in Ischemic Brain Damage

Hervé Boutin, R.A. LeFeuvre, Reiko Horai et al. · Journal of Neuroscience · 2001 · 432 citations · Full text

Immunology, Cell Death, Cerebral Vascular Regulation +21