Constituents of Crinoidea. 1. Isolation and Structure of Inositolphosphoceramide from the Feather Star Comanthus japonica.

Abstract

An inositolphosphoceramide molecular species, tentatively named CJP1, has been obtained from the feather star Comanthus japonica, which belong to the class of crinoidea of phylum echinodermata of deuterostomia. On the basis of chemical and spectroscopic evidence, the structure of CJP1 was determined as D-myo-inositol-1-O-phosphoceramide, which contained a C16 : 1 sphingosine and a C22 : 0, C24 : 0 normal fatty acid. The same type of sphingolipid has been obtained from plants and protostomia but not yet from deuterostomia. This is the first report on the isolation and structure elucidation of inositolphosphoceramide from deuterostomia.