Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice. - Concepedia

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Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice.

46

Citations

52

References

2003

Year

Katarzyna Kozar, Rafał Kamiński, Tomasz Świtaj, Tomasz Ołdak, Eugeniusz K Machaj, Piotr J. Wysocki, Andrzej Maćkiewicz, Witold Lasek, Marek Jakóbisiak, Jakub Gołąb

Abstract

This study provides the first evidence that antitumor effects of DAC can be strongly potentiated by IL-12 and could be beneficial in an effective low-dose-based antitumor therapy.

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