Cadherin-13, a Mediator of Calcium-Dependent Cell-Cell Adhesion, Is Silenced by Methylation in Chronic Myeloid Leukemia and Correlates With Pretreatment Risk Profile and Cytogenetic Response to Interferon Alfa - Concepedia

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Cadherin-13, a Mediator of Calcium-Dependent Cell-Cell Adhesion, Is Silenced by Methylation in Chronic Myeloid Leukemia and Correlates With Pretreatment Risk Profile and Cytogenetic Response to Interferon Alfa

96

Citations

38

References

2003

Year

José Román‐Gómez, Juan A. Castillejo, Antonio Jiménez, Francisco Cervantes, Concepción Boqué, Lourdes Hermosín, Ángel León, A Grañena, Dolors Colomer, Anabel Heiniger,

Journal of Clinical Oncology

Abstract

Our data indicate that the silencing of CDH13 expression by aberrant promoter methylation occurs at an early stage in CML pathogenesis and probably influences the clinical behavior of the disease.

References

	Year	Citations
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. James G. Herman, Jeremy R. Graff, Sanna Myöhänen, Proceedings of the National Academy of Sciences Epigenetic ChangeGeneticsDna MethylationDna AnalysisMolecular Biology	1996	5.6K
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer Elizabeth E. Cameron, Kurtis E. Bachman, Sanna Myöhänen, Nature Genetics Histone ModificationsChromatinRadiation OncologyChromatin RemodelingEpigenetic Change	1999	1.9K
The molecular biology of chronic myeloid leukemia Michael W. Deininger, John M. Goldman, Junia V. Melo Blood	2000	1.6K
Prognostic discrimination in "good-risk" chronic granulocytic leukemia JE Sokal, Cox Eb, Michele Baccarani, Blood	1984	1K
Prognostic discrimination in "good-risk" chronic granulocytic leukemia JE Sokal, Cox Eb, Michele Baccarani, Blood	1984	954
Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor Luciano Di Croce, Veronica A. Raker, Massimo Corsaro, Science Epigenetic ChangeGeneticsDna MethylationMolecular BiologyGene Transcription	2002	778
Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia A Bedi, BA Zehnbauer, SJ Sharkis, Blood	1994	496
The cadherin-catenin adhesion system in signaling and cancer Maralice Conacci‐Sorrell, Jacob Zhurinsky, Avri Ben‐Ze'ev Journal of Clinical Investigation Signaling PathwayCell AdhesionCell-matrix InteractionCadherin-catenin Adhesion SystemMedicine	2002	458
Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia M. Y. Gordon, C. Dowding, Graham P. Riley, Nature Altered Adhesive InteractionsHematological MalignancyBone Marrow FailureChronic Myeloid LeukaemiaMedicine	1987	450
Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway. Lorri Puil, J. Liu, G Gish, The EMBO Journal Signal TransductionSignaling PathwayCell RegulationMolecular RegulationReceptor Tyrosine Kinase	1994	447

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