Blood · 2000 · 1.6K citations · 199 references
MedicineMolecular BiologyOncologyHematologic OncologyMolecular Cell BiologyMolecular OncologyCancer EpigeneticsCancer GenomicsHematologic MalignanciesMolecular CytogeneticsMyc Family OncogenesMyeloid-derived Suppressor CellsBcr-abl1 Fusion GeneChronic LeukemiasChronic Myeloid Leukemia TherapyLeukemia CytogeneticsLeukemia Pathology
Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph) chromosome in 19601 as the first consistent chromosomal abnormality associated with a specific type of leukemia was a breakthrough in cancer biology. It took 13 years
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Induction of apoptosis in fibroblasts by c-myc protein
Gérard I. Evan, Andrew H. Wyllie, Christopher S. Gilbert et al. · Cell · 1992 · 3K citations