Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity and glucose intolerance in aged rats

Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

Dennis Huszar, Catherine Lynch, Victoria Fairchild-Huntress et al. · Cell · 1997 · 3K citations · Full text

Medicine, Endocrinology, Neuroscience +11

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

Wei Fan, Bruce A. Boston, Robert A. Kesterson et al. · Nature · 1997 · 1.9K citations

Life Sciences, Neurobiology, Neuroscience +14

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

Heiko Krude, Heike Biebermann, W. A. P. Luck et al. · Nature Genetics · 1998 · 1.7K citations

Life Sciences, Endocrinology, Genetics +17

Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action

Robert Frederich, A. Hamann, Stephen Anderson et al. · Nature Medicine · 1995 · 1.7K citations

Life Sciences, Endocrinology, Nutritional Sciences +15

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Guangping Gao, Mauricio R. Alvira, Lili Wang et al. · Proceedings of the National Academy of Sciences · 2002 · 1.5K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +15