Concepedia

Dynamic Chemotherapy-Induced Upregulation of CXCR4 Expression: A Mechanism of Therapeutic Resistance in Pediatric AML

Edward Allan R. Sison, Emily McIntyre, Daniel Magoon, Patrick A. Brown

Molecular Cancer Research · 2013 · 98 citations · 46 references

DOIFull text

Open access

Abstract

CXCR4 may be a biomarker for the stratification and optimal treatment of patients using CXCR4 inhibitors.

References

46

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

Simón Méndez‐Ferrer, Tatyana V. Michurina, Francesca Ferraro et al. · Nature · 2010 · 3.3K citations

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Dependence of Human Stem Cell Engraftment and Repopulation of NOD/SCID Mice on CXCR4

Amnon Peled, Isabelle Petit, Órit Kollet et al. · Science · 1999 · 1.7K citations

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

Conrad C. Bleul, Robert C. Fuhlbrigge, José M. Casasnovas et al. · The Journal of Experimental Medicine · 1996 · 1.5K citations · Full text

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Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

Marc H.G.P. Raaijmakers, Siddhartha Mukherjee, Shangqin Guo et al. · Nature · 2010 · 1.1K citations

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Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

Douglas Tkachuk, Sabine Köhler, Michael L. Cleary · Cell · 1992 · 928 citations

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