Concepedia

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

Karla L. Lightfield, Jenny Persson, Sky W. Brubaker, Chelsea E. Witte, Jakob von Moltke, Eric A. Dunipace, Thomas Henry, Yaohui Sun, Dragana Cado, William F. Dietrich,

Nature Immunology · 2008 · 493 citations · 46 references

DOIFull text

Open access

Concepts

References

46

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations

, , +11

Cryopyrin activates the inflammasome in response to toxins and ATP

Sanjeev Mariathasan, David S. Weiss, Kim Newton et al. · Nature · 2006 · 3K citations

, , +7

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

, , +13

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

Catherine Dostert, Virginie Pétrilli, Robin van Bruggen et al. · Science · 2008 · 2.7K citations · Full text

, , +17

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Annett Halle, Veit Hornung, Gabor C. Petzold et al. · Nature Immunology · 2008 · 2.4K citations · Full text

, , +13