Concepedia

Bcl-2 Suppresses Sarcoplasmic/Endoplasmic Reticulum Ca <sup>2+</sup> -ATPase Expression in Cystic Fibrosis Airways

Shama Ahmad, Aftab Ahmad, Elena S. Dremina, Victor S. Sharov, Xiaoling Guo, Tara N. Jones, Joan E. Loader, Jason R. Tatreau, Anne-Laure Perraud, Christian Schöneich,

American Journal of Respiratory and Critical Care Medicine · 2009 · 32 citations · 53 references

DOIFull text

Open access

Abstract

Reduced SERCA2 expression may alter calcium signaling and apoptosis in CF. These findings decrease the likelihood of therapeutic benefit of SERCA inhibition in CF.

References

53

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M. Leslie Fulcher, Sherif E. Gabriel, Kimberlie A. Burns et al. · Humana Press eBooks · 2004 · 628 citations

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NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis

Cun-Yu Wang, Denis C. Guttridge, Marty W. Mayo et al. · Molecular and Cellular Biology · 1999 · 582 citations · Full text

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Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects

Marie E. Egan, Marilyn Pearson, Scott A. Weiner et al. · Science · 2004 · 559 citations

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Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium.

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Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cells

Marie E. Egan, Judith Glöckner-Pagel, Catherine Ambrose et al. · Nature Medicine · 2002 · 203 citations

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