Bcl-2 Suppresses Sarcoplasmic/Endoplasmic Reticulum Ca <sup>2+</sup> -ATPase Expression in Cystic Fibrosis Airways - Concepedia

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Bcl-2 Suppresses Sarcoplasmic/Endoplasmic Reticulum Ca <sup>2+</sup> -ATPase Expression in Cystic Fibrosis Airways

DOI Full Paper Access

32

Citations

53

References

2009

Year

Shama Ahmad, Aftab Ahmad, Elena S. Dremina, Victor S. Sharov, Xiaoling Guo, Tara N. Jones, Joan E. Loader, Jason R. Tatreau, Anne-Laure Perraud, Christian Schöneich,

American Journal of Respiratory and Critical Care Medicine

Abstract

Reduced SERCA2 expression may alter calcium signaling and apoptosis in CF. These findings decrease the likelihood of therapeutic benefit of SERCA inhibition in CF.

References

	Year	Citations
Well-Differentiated Human Airway Epithelial Cell Cultures M. Leslie Fulcher, Sherif E. Gabriel, Kimberlie A. Burns, Humana Press eBooks AsthmaInflammationLung InflammationRespiratory ToxicologyInhalation Toxicology	2004	628
NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis Cun-Yu Wang, Denis C. Guttridge, Marty W. Mayo, Molecular and Cellular Biology MitophagyApoptosisImmunologyCell DeathPathology	1999	582
Curcumin, a Major Constituent of Turmeric, Corrects Cystic Fibrosis Defects Marie E. Egan, Marilyn Pearson, Scott A. Weiner, Science Molecular PharmacologyFibrosisSignal TransductionMolecular PhysiologyMedicine	2004	559
Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium. Marina Arai, Norman R. Alpert, D H MacLennan, Circulation Research Cardiac MuscleHuman Heart FailureHeart FailureStructural Heart DiseaseCellular Physiology	1993	478
Calcium-pump inhibitors induce functional surface expression of ΔF508-CFTR protein in cystic fibrosis epithelial cells Marie E. Egan, Judith Glöckner-Pagel, Catherine Ambrose, Nature Medicine FibrosisMolecular PhysiologySignal TransductionCalcium-pump InhibitorsδF508-cftr Protein	2002	203
Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation Gavin M. Braunstein, Richard M. Roman, John Clancy, Journal of Biological Chemistry Signal TransductionMolecular PhysiologyBiochemistryHyperpolarization (Biology)Cell Signaling	2001	194
Modulation of endoplasmic reticulum calcium pump by Bcl-2 Tuan H. Kuo, Hyeong-Reh Choi Kim, Yingjie Yu, Oncogene Molecular PhysiologySignal TransductionPhysiologyEndocytic PathwayIntracellular Trafficking	1998	186
NF-κB activates Bcl-2 expression in t(14;18) lymphoma cells Caroline A. Heckman, John W Mehew, Linda M. Boxer Oncogene Lymphoid NeoplasiaCancer ImmunosurveillanceLymphoma CellsImmunologyTumor Immunity	2002	182
Innate immune response in CF airway epithelia: hyperinflammatory? Terry E. Machen American Journal of Physiology-Cell Physiology	2006	179
Calreticulin Differentially Modulates Calcium Uptake and Release in the Endoplasmic Reticulum and Mitochondria Serge Arnaudeau, Maud Frieden, Kimitoshi Nakamura, Journal of Biological Chemistry	2002	176

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