Time‐Resolved NMR Spectroscopic Studies of DNA i‐Motif Folding Reveal Kinetic Partitioning

Abstract

Get the zipper right: Time-resolved NMR spectroscopy measurements reveal kinetic partitioning for pH-induced DNA i-motif formation (see scheme). The data characterize the folding pathway of i-motifs and provide a biophysical based description of pH-dependent folding processes as utilized in live-cell pH sensors.