Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF

A protein factor essential for microtubule assembly.

Murray Weingarten, Arthur H. Lockwood, S Y Hwo et al. · Proceedings of the National Academy of Sciences · 1975 · 3K citations · Full text

Protein Function, Protein Assembly, Protein Folding +15

A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity

Hyejin Kang, Erin M. Schuman · Science · 1996 · 969 citations

Local Protein Synthesis, Synaptic Plasticity, Neurotrophin-induced Plasticity +14

Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments

Alejandra del C. Alonso, Tanweer Zaidi, Michal Novák et al. · Proceedings of the National Academy of Sciences · 2001 · 959 citations · Full text

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

Heidi Phillips, Jeanne M. Hains, Mark Armanini et al. · Neuron · 1991 · 917 citations

Alzheimer's Disease, Bdnf Mrna, Dementia +8

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding

Jacek Biernat, N. Gustke, Gerard Drewes et al. · Neuron · 1993 · 787 citations

Protein Function, Signal Transduction, Medicine +12