HSF2 binds to the Hsp90, Hsp27, and c-Fos promoters constitutively and modulates their expression

Repression of Heat Shock Transcription Factor HSF1 Activation by HSP90 (HSP90 Complex) that Forms a Stress-Sensitive Complex with HSF1

Jiangying Zou, Yongle Guo, Toumy Guettouche et al. · Cell · 1998 · 1.2K citations

Transcriptional Regulation, Signal Transduction, Cell Regulation +12

Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.

Kevin D. Sarge, Shawn P. Murphy, Richard I. Morimoto · Molecular and Cellular Biology · 1993 · 876 citations · Full text

Involves Oligomerization, Genetics, Molecular Biology +21

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones

William B. Pratt · Endocrine Reviews · 1997 · 638 citations

Inflammation, Steroid Receptor Interactions, Signal Transduction +12

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy

Oleg V. Evgrafov, Irina Mersiyanova, Joy Irobi et al. · Nature Genetics · 2004 · 581 citations · Full text

Neurodegenerative Diseases, Neurological Disorder, Medicine +7

jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

J. Schütte, Jean Viallet, Marion M. Nau et al. · Cell · 1989 · 487 citations

Jun-b Inhibits, Signal Transduction, Cell Regulation +11