Kevin D. Sarge

Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.

Kevin D. Sarge, Shawn P. Murphy, Richard I. Morimoto · Molecular and Cellular Biology · 1993 · 876 citations · Full text

Involves Oligomerization, Genetics, Molecular Biology +21

Transcriptional regulation of heat shock genes. A paradigm for inducible genomic responses.

R.I. Morimoto, Kevin D. Sarge, Klara Abravaya · Journal of Biological Chemistry · 1992 · 416 citations · Full text

Ideal Paradigm, Molecular Regulation, Genetics +21

Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability.

Kevin D. Sarge, Vincenzo Zimarino, Karyn Holm et al. · Genes & Development · 1991 · 381 citations · Full text

Molecular Regulation, Genetics, Molecular Biology +17

In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation.

Dick D. Mosser, Paul T. Kotzbauer, Kevin D. Sarge et al. · Proceedings of the National Academy of Sciences · 1990 · 293 citations

Molecular Regulation, Molecular Biology, Biochemical Conditions +19

Activation of Heat Shock Factor 2 during Hemin-Induced Differentiation of Human Erythroleukemia Cells

Lea Sistonen, Kevin D. Sarge, Benette Phillips et al. · Molecular and Cellular Biology · 1992 · 275 citations · Full text

Human Hsp70 Promoter, Immunology, Blood Cell +18