Concepedia

Renal cilia display length alterations following tubular injury and are present early in epithelial repair

Elizabeth Verghese, Raphael Weidenfeld, John F. Bertram, Sharon D. Ricardo, James A. Deane

Nephrology Dialysis Transplantation · 2007 · 98 citations · 17 references

DOIFull text

Open access

Abstract

We propose roles for the renal cilium in responding to changes in the renal environment caused by injury, and in the repair process that re-establishes the epithelial layer of the damaged renal tubule.

References

17

Update on Mechanisms of Ischemic Acute Kidney Injury

Prasad Devarajan · Journal of the American Society of Nephrology · 2006 · 1K citations

Bending the MDCK Cell Primary Cilium Increases Intracellular Calcium

K. R. Spring · The Journal of Membrane Biology · 2001 · 808 citations

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Monoclonal antibodies specific for an acetylated form of alpha-tubulin recognize the antigen in cilia and flagella from a variety of organisms.

G Piperno, Margaret T. Fuller · The Journal of Cell Biology · 1985 · 761 citations · Full text

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Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

Matias Simons, Joachim Gloy, Athina Ganner et al. · Nature Genetics · 2005 · 752 citations · Full text

, , +11

Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.

Ralph Witzgall, Dennis Brown, Christoph Schwarz et al. · Journal of Clinical Investigation · 1994 · 604 citations · Full text

, , +20