Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases

Peter H. Sayre, Janet Finer-Moore, Timothy A. Fritz, D. Biermann, Susan B. Gates, W.C. MacKellar, Vinod F. Patel, R. M. Stroud

Journal of Molecular Biology · 2001 · 60 citations · 49 references

Concepts

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