Interaction of NADPH oxidase 1 with Toll-like receptor 2 induces migration of smooth muscle cells

Abstract

These data suggest that Nox1 plays an important role in TLR2-mediated intracellular H2O2 generation, activation of matrix metalloprotease 2, and secretion of pro-inflammatory cytokines, which in turn stimulate MASMC migration and vascular remodelling.