Concepedia

CHEK2*1100delC is not an important high-risk gene in families with hereditary prostate cancer in southern Sweden

Magnus Wagenius, Åke Borg, Lovisa Johansson, Aleksander Giwercman, Ola Bratt

Scandinavian Journal of Urology and Nephrology · 2006 · 17 citations · 13 references

DOI

Abstract

The CHEK2 1100delC mutation is not a clinically important high-risk gene for hereditary prostate cancer susceptibility in the population of southern Sweden.

References

13

Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland

Paul Lichtenstein, Niels V. Holm, Pia K. Verkasalo et al. · New England Journal of Medicine · 2000 · 4.1K citations

Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations

Deborah J. Thompson, Richard S. Houlston, Catherine Phelan · Nature Genetics · 2002 · 1.1K citations · Full text

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Chk2/hCds1 functions as a DNA damage checkpoint in G<sub>1</sub>by stabilizing p53

Nabil Chehab, Asra Malikzay, Michael Appel et al. · Genes & Development · 2000 · 784 citations · Full text

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hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

Jong‐Soo Lee, Kimberly M. Collins, Alexandra L. Brown et al. · Nature · 2000 · 528 citations

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CHEK2*1100delC and Susceptibility to Breast Cancer: A Collaborative Analysis Involving 10,860 Breast Cancer Cases and 9,065 Controls from 10 Studies

The American Journal of Human Genetics · 2004 · 471 citations · Full text

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