Spatial cognition and the human navigation network in AD and MCI

Amy R. Deipolyi, Katherine P. Rankin, Lennart Mucke, Bruce L. Miller, Maria‐Luisa Gorno‐Tempini

Neurology · 2007 · 246 citations · 45 references

Abstract

The navigation disability in Alzheimer disease and mild cognitive impairment (MCI) involves a selective impairment of spatial cognition and is associated with atrophy of the right-lateralized navigation network. Extensive spatial impairments in MCI suggest that navigation tests may provide early markers of cognitive and neural damage.

References

45