High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam, Russell M. Lebovitz, R G Roeder · Nucleic Acids Research · 1983 · 11.6K citations · Full text

Engineering, Rna Polymerase Ii, Isolated Mammalian Nuclei +19

Doxorubicin pathways

Caroline F. Thorn, Connie Oshiro, Sharon Marsh et al. · Pharmacogenetics and Genomics · 2010 · 1.6K citations · Full text

Author Information, Literary Theory, Humanities +6

In Vitro Cytotoxicity of Nanoparticles in Mammalian Germline Stem Cells

Laura K. Braydich‐Stolle, Saber M. Hussain, John J. Schlager et al. · Toxicological Sciences · 2005 · 1.2K citations · Full text

Nanoparticles, Engineering, Nanotoxicology +16

Microarrays of cells expressing defined cDNAs

Junaid Ziauddin, David M. Sabatini · Nature · 2001 · 914 citations

Functional Genomics, Dna Microarrays, Gene Expression +4

Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins

Helga H.J. Gerets, Karen Tilmant, Brigitte Gerin et al. · Cell Biology and Toxicology · 2012 · 664 citations · Full text

Pathology, Heparg Cells, Oxidative Stress +23