Concepedia

Loss of Parafibromin Immunoreactivity Is a Distinguishing Feature of Parathyroid Carcinoma

Min‐Han Tan, Carl Morrison, Pengfei Wang, Ximing J. Yang, Carola J. Haven, Chun Zhang, Ping Zhao, Maria Tretiakova, Eeva Korpi-Hyövälti, John Burgess,

Clinical Cancer Research · 2004 · 244 citations · 46 references

DOIFull text

Open access

Abstract

Parafibromin is a promising molecular marker for diagnosing parathyroid carcinoma. The similar loss of parafibromin immunoreactivity in HPT-JT syndrome-related adenomas suggests that this is a pivotal step in parathyroid tumorigenesis.

References

46

Two-sided confidence intervals for the single proportion: comparison of seven methods

Robert G. Newcombe · Statistics in Medicine · 1998 · 5K citations

Tissue microarrays for high-throughput molecular profiling of tumor specimens

Juha Kononen, Lukas Bubendorf, Anne Kallionimeni et al. · Nature Medicine · 1998 · 4.1K citations

, , +6

Users' Guides to the Medical Literature

Roman Jaeschke · JAMA · 1994 · 2.2K citations

, , +17

Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group

Roman Jaeschke · JAMA · 1994 · 1.8K citations

, , +20

HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome

John D. Carpten, Christiane M. Robbins, Andrea Villablanca et al. · Nature Genetics · 2002 · 742 citations

, , +2