Loss of Parafibromin Immunoreactivity Is a Distinguishing Feature of Parathyroid Carcinoma - Concepedia

Concepedia

Publication | Open Access

Loss of Parafibromin Immunoreactivity Is a Distinguishing Feature of Parathyroid Carcinoma

DOI Full Paper Access

244

Citations

46

References

2004

Year

Min‐Han Tan, Carl Morrison, Pengfei Wang, Ximing J. Yang, Carola J. Haven, Chun Zhang, Ping Zhao, Maria Tretiakova, Eeva Korpi-Hyövälti, John Burgess,

Clinical Cancer Research

Abstract

Parafibromin is a promising molecular marker for diagnosing parathyroid carcinoma. The similar loss of parafibromin immunoreactivity in HPT-JT syndrome-related adenomas suggests that this is a pivotal step in parathyroid tumorigenesis.

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