Concepedia

p53 Alterations Predict Tumor Response to Neoadjuvant Chemotherapy in Head and Neck Squamous Cell Carcinoma: A Prospective Series

Arnauld Cabelguenne, Hélène Blons, Isabelle de Waziers, Françoise Carnot, Anne‐Marie Houllier, Thierry Soussi, Daniel Brasnu, Philippe Beaune, O. Laccourreye, Pierre Laurent‐Puig

Journal of Clinical Oncology · 2000 · 193 citations · 44 references

DOI

Abstract

This prospective study suggests that p53 status may be a useful indicator of response to neoadjuvant chemotherapy in HNSCC.

References

44

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Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

Marc S. Greenblatt, W P Bennett, Monica Hollstein et al. · PubMed · 1994 · 3.5K citations

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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Induction Chemotherapy plus Radiation Compared with Surgery plus Radiation in Patients with Advanced Laryngeal Cancer

New England Journal of Medicine · 1991 · 2.7K citations · Full text

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

Yunje Cho, Svetlana S. Gorina, Philip D. Jeffrey et al. · Science · 1994 · 2.5K citations

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