Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS

References

Page 1

	Year	Citations
Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors Yasuo Uchida, Sumio Ohtsuki, Yuki Katsukura, Journal of Neurochemistry Human Bbb FunctionNeurochemical BiomarkersPeptide ScienceProteomic TechnologyMolecular Pharmacology	2011	891
Near Completely Humanized Liver in Mice Shows Human-Type Metabolic Responses to Drugs Chise Tateno, Yasumi Yoshizane, Naomi Saito, American Journal Of Pathology Metabolic SyndromeHepatologyBiochemistryMedicineLiver Physiology	2004	541
Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria Junichi Kamiie, Sumio Ohtsuki, Ryo Iwase, Pharmaceutical Research Membrane TransporterProteinlipid InteractionBiochemistryNatural SciencesMembrane Transport	2008	476
Simultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and Activities Sumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami, Drug Metabolism and Disposition	2011	428
Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels Ramzi Shawahna, Yasuo Uchida, Xavier Declèves, Molecular Pharmaceutics	2011	364
Simultaneous Absolute Quantification of 11 Cytochrome P450 Isoforms in Human Liver Microsomes by Liquid Chromatography Tandem Mass Spectrometry with In Silico Target Peptide Selection Hirotaka Kawakami, Sumio Ohtsuki, Junichi Kamiie, Journal of Pharmaceutical Sciences BiochemistryGas ChromatographyMedicineLiver PhysiologySimultaneous Absolute Quantification	2010	165
Absolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human Hepatocytes Olaf Schaefer, Sumio Ohtsuki, Hirotaka Kawakami, Drug Metabolism and Disposition	2011	132
EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER Miki Katoh, Tomohito Matsui, Miki Nakajima, Drug Metabolism and Disposition	2004	114
EXPRESSION OF HUMAN PHASE II ENZYMES IN CHIMERIC MICE WITH HUMANIZED LIVER Miki Katoh, Tomohito Matsui, Hirotoshi Okumura, Drug Metabolism and Disposition	2005	101
Morphological and microarray analyses of human hepatocytes from xenogeneic host livers Chise Tateno, Fuyuki Miya, Kenjiro Wake, Laboratory Investigation HepatologyMedicineLiver PhysiologyHistopathologyHepatitis	2012	66

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