Knockout Mice Reveal a Role for P2Y6 Receptor in Macrophages, Endothelial Cells, and Vascular Smooth Muscle Cells

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

Sharon E Haynes, Gunther Hollopeter, Guang Yang et al. · Nature Neuroscience · 2006 · 1.5K citations

Medicine, P2y12 Receptor, Brain-immune Interaction +6

UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

Schuichi Koizumi, Yukari Shigemoto‐Mogami, Kaoru Nasu‐Tada et al. · Nature · 2007 · 797 citations

Inflammation, Medicine, Immunology +7

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y1 receptor–null mice

Catherine Léon, Béatrice Hechler, Monique Freund et al. · Journal of Clinical Investigation · 1999 · 447 citations · Full text

Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice

Jean-Etienne Fabre, MyTrang Nguyen, Anne M. Latour et al. · Nature Medicine · 1999 · 432 citations

Inflammation, Thrombosis, Platelet Aggregation Inhibitors +15

Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs

Carolyn Foster, Dina M. Prosser, Jacqueline Agans et al. · Journal of Clinical Investigation · 2001 · 413 citations · Full text

Immunology, Pharmacotherapy, Platelet Aggregation +21