Blocking Bcl-2 Leads to Autophagy Activation and Cell Death of the HEPG2 Liver Cancer Cell Line

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark et al. · Journal of Biological Chemistry · 2007 · 4.5K citations · Full text

Mitophagy, Facilitate Degradation, Molecular Biology +20

Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy

Sophie Pattingre, Amina Tassa, Xueping Qu et al. · Cell · 2005 · 3.4K citations · Full text

Cell Autophagy, Autophagy, Cell Death +5

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

Tatsuya Saitoh, Naonobu Fujita, Myoung Ho Jang et al. · Nature · 2008 · 2K citations

Inflammation, Cytokine, Cell Autophagy +7

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

Ken Cadwell, John Y. Liu, Sarah L. Brown et al. · Nature · 2008 · 1.5K citations · Full text

Autophagy Gene Atg16l1, Mitophagy, Cell Autophagy +9

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

Yongjie Wei, Sophie Pattingre, Sangita C. Sinha et al. · Molecular Cell · 2008 · 1.3K citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +6