Cox‐2 Inhibitor Attenuates NO‐Induced nNOS in Rat Caudal Trigeminal Nucleus

Abstract

These findings suggest that metabolites deriving from COX-2 (but not COX-1) may be the most important factors in the NTG-induced nNOS expression. These data could help to better understand the pathogenesis of headaches and the action of antimigraine drugs.

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