Concepedia

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

Takayuki Kondo, Masashi Asai, Kayoko Tsukita, Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada, Keiko Imamura, Naohiro Egawa, Naoki Yahata, Keisuke Okita,

Cell stem cell · 2013 · 752 citations · 24 references

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Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva et al. · Nature · 2002 · 4.3K citations

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Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Ganesh M. Shankar, Shaomin Li, Tapan Mehta et al. · Nature Medicine · 2008 · 3.7K citations · Full text

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RETRACTED ARTICLE: A specific amyloid-β protein assembly in the brain impairs memory

Sylvain Lesné, Ming Teng Koh, Linda Kotilinek et al. · Nature · 2006 · 2.8K citations

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A more efficient method to generate integration-free human iPS cells

Keisuke Okita, Yasuko Matsumura, Yoshiko Sato et al. · Nature Methods · 2011 · 2.1K citations · Full text

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Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

Mason A. Israel, Shauna H. Yuan, Cédric Bardy et al. · Nature · 2012 · 1.3K citations

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