Antitumor activity of a novel orally effective nucleoside, 1-(2-deoxy-2-fluoro-4-thio-β-d-arabinofuranosyl)cytosine

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

Life Sciences, Cell Biology, Apoptosis +14

Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).

Larry W. Hertel, G B Boder, Julian S. Kroin et al. · PubMed · 1990 · 683 citations

Medicine, Oncology, Pharmacology +11

Nucleosides and Nucleotides

Kazunobu Miura, Masatoshi SHIGA, Tohru Ueda · The Journal of Biochemistry · 1973 · 487 citations

Pharmacy, Biochemistry, Chemistry +15

Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides

Kyoichi A. Watanabe, U. REICHMAN, Kosaku Hirota et al. · Journal of Medicinal Chemistry · 1979 · 268 citations

Life Sciences, Chemistry, Medicinal Chemistry +15

Preclinical in vivo activity of 2',2'-difluorodeoxycytidine (Gemcitabine) against human head and neck cancer.

B.J.M. Braakhuis, Guus A.M.S. van Dongen, J. B. Vermorken et al. · PubMed · 1991 · 136 citations

Medicine, Oncology, Pharmacology +11