The expression of multidrug resistance-associated protein (MRP) in pancreatic adenocarcinoma cell lines

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

Medicine, Molecular Biology, Oncology +16

The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

Inka Leier, Gabriele Jedlitschky, Ulrike Buchholz et al. · Journal of Biological Chemistry · 1994 · 856 citations · Full text

Medicine, Biochemistry, Pharmacology +14

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

G J Zaman, M J Flens, Manuel R. van Leusden et al. · Proceedings of the National Academy of Sciences · 1994 · 692 citations · Full text

Medicine, Oncology, Pharmacology +17

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

Guido J.R. Zaman, J. Lankelma, Olaf van Tellingen et al. · Proceedings of the National Academy of Sciences · 1995 · 502 citations · Full text

Medicine, Oncology, Pharmacology +16

Overlapping phenotypes of multidrug resistance among panels of human cancer-cell lines

Miguel Izquierdo, Robert H. Shoemaker, Marcel J. Flens et al. · International Journal of Cancer · 1996 · 212 citations

Medicine, Oncology, Pharmacology +14