Interactions of CB1 and mGlu5 receptor antagonists in food intake, anxiety and memory models in rats

The endogenous cannabinoid system controls extinction of aversive memories

Giovanni Marsicano, Carsten T. Wotjak, Shahnaz Christina Azad et al. · Nature · 2002 · 1.7K citations

Life Sciences, Neuroscience, Pharmacology +14

Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity

Richard H. Porter, Georg Jaeschke, Will Spooren et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 314 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory

Patrizia Campolongo, Benno Roozendaal, Viviana Trezza et al. · Proceedings of the National Academy of Sciences · 2009 · 293 citations · Full text

Medicine, Neuroscience, Pharmacology +13

Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release

Houman Homayoun, Mark R. Stefani, Barbara W. Adams et al. · Neuropsychopharmacology · 2004 · 253 citations

Life Sciences, Neurobiology, Neuroscience +12

Drug-Induced Psychosis: How to Avoid Star Gazing in Schizophrenia Research by Looking at More Obvious Sources of Light

Alessandra Paparelli, Marta Di Forti, Paul D. Morrison et al. · Frontiers in Behavioral Neuroscience · 2011 · 217 citations · Full text

Medicine, Pharmacology, Psychiatry +13