Synthesis and single enzyme activity of a clicked lipase–BSA hetero-dimer

Nikos S. Hatzakis, Hans Engelkamp, Kelly Velonia, Johan Hofkens, Peter C. M. Christianen, Allan Svendsen, Shamkantr A. Patkar, Jesper Vind, J. C. Maan, Alan E. Rowan,

Chemical Communications · 2006 · 77 citations · 24 references

Concepts

Abstract

Click chemistry is used to construct a novel lipase-BSA hetero-dimer, in which the latter protein acts as a foot enabling the anchoring of the enzyme onto the surface for single enzyme studies.

References

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