Targeted Mutagenesis of Tsix Leads to Nonrandom X Inactivation

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

Mary F. Lyon · Nature · 1961 · 4K citations

Life Sciences, Genetics, Molecular Genetics +12

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 4K citations

Life Sciences, Genetics, Molecular Biology +14

The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

Carolyn J. Brown, Brian Hendrich, Jim L. Rupert et al. · Cell · 1992 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +10

Requirement for Xist in X chromosome inactivation

Graeme D. Penny, Graham F. Kay, Steven A. Sheardown et al. · Nature · 1996 · 1.2K citations

Life Sciences, Genetics, Molecular Genetics +6

The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus

Neil Brockdorff, Alan Ashworth, Graham F. Kay et al. · Cell · 1992 · 1K citations

Life Sciences, Genetics, Molecular Genetics +7