Chemical Communications · 2014 · 64 citations · 34 references
Life SciencesChemistryMicrobiologyDrug DiscoveryGlycobiologyGlycan BiosynthesisGlycan StructureMicrobial GlycobiologyProtein GlycosylationGlycan Building Block SynthesisLectin InteractionsLectin RecognitionMicrobial LectinsMultivalent Glycan RecognitionMultivalent Ligands
Both convergent and divergent strategies for the synthesis of "onion peel" glycodendrimers are reported which resulted in one of the best multivalent ligands known against the virulent factor from a bacterial lectin isolated from Pseudomonas aeruginosa.
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