Nucleic Acids Research · 2012 · 130 citations · 24 references
Life SciencesBioinformaticsMicrobiologyGenomicsMicrobial GeneticsMicrobial MetabolismBiosynthetic Gene ClustersPolyketide BiosynthesisBiosynthetic Gene Cluster AnalysisData ConsistencyGene Cluster AnnotationNon-ribosomal Peptide BiosynthesisPolyketide Synthase Gene ClustersPolyketide Synthase Gene DiscoveryPolyketide Synthase PathwaysSequence Repository Construction
ClusterMine360 (http://www.clustermine360.ca/) is a database of microbial polyketide and non-ribosomal peptide gene clusters. It takes advantage of crowd-sourcing by allowing members of the community to make contributions while automation is used to help achieve high data consistency and quality. The database currently has >200 gene clusters from >185 compound families. It also features a unique sequence repository containing >10 000 polyketide synthase/non-ribosomal peptide synthetase domains. The sequences are filterable and downloadable as individual or multiple sequence FASTA files. We are confident that this database will be a useful resource for members of the polyketide synthases/non-ribosomal peptide synthetases research community, enabling them to keep up with the growing number of sequenced gene clusters and rapidly mine these clusters for functional information.
24
MUSCLE: multiple sequence alignment with high accuracy and high throughput
R. C. Edgar · Nucleic Acids Research · 2004 · 46.5K citations · Full text
Marnix H. Medema, Kai Blin, Peter Cimermančič et al. · Nucleic Acids Research · 2011 · 2K citations · Full text
PubChem: a public information system for analyzing bioactivities of small molecules
Y. Wang, J. Xiao, Tuğba Önal-Süzek et al. · Nucleic Acids Research · 2009 · 1.5K citations · Full text