Organic and Medicinal Chemistry Letters · 2014 · 57 citations · 9 references
Life SciencesBiochemistryMedicinal ChemistryChromatographic AnalysisFood AnalysisMass Spectrometric AnalysisBioactive Natural ProductsEssential Fatty AcidsMedicinal Plant KnowledgeMedicinal PlantsMetabolite ExtractionMetabolite IdentificationExtraction Of Bioactive CompoundsHerbaceous Plant FormMass Spectral FragmentationMedicinal Plant ResourcesMusculoskeletal DisordersNatural Product ExtractionPhenolic Content AnalysisPlant Extract Antioxidants
BACKGROUND: Macrotyloma uniflorum Linn (Fabaceae) is a herbaceous plant with annual branches. It is used in kidney stones, inflamed joints, fever, musculoskeletal disorders, sinus wounds and localized abdominal tumors. It is reported as an antioxidant and nutraceutical (forage and food). GC-MS analysis of ethanol extract has led to identification of twenty-eight compounds from M. uniflorum by comparison of their retention indices and mass spectra fragmentation patterns with those stored on the GC-MS computer library. RESULTS: The main constituents identified were mome inositol, ethyl alpha-d-glucopyranoside, n- hexadecanoic acid, linoleic acid (9, 12-octadecadienoic acid), its esters and ethyl derivatives, Vitamin E, stigmasterol and 3-beta-stigmast-5-en-3-ol. CONCLUSIONS: The extracts are rich in linoleic acid and its esters, mome inositol and ethyl alpha-d-glucopyranoside; therefore, this plant can be medicinally beneficial as an antioxidant, in diabetes and its related disorders.
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