Concepedia

Discovery of N-Hydroxy-2-(2-oxo-3-pyrrolidinyl)acetamides as potent and selective inhibitors of tumor necrosis factor-α converting enzyme (TACE)

James J.‐W. Duan, Zhonghui Lu, Chu‐Biao Xue, Xiaohua He, Jennifer L. Seng, John Roderick, Zelda R. Wasserman, Rui‐Qin Liu, Maryanne Covington, Ronald L. Magolda,

Bioorganic & Medicinal Chemistry Letters · 2003 · 37 citations · 23 references

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Concepts

References

23

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

Roy A. Black, Charles T. Rauch, Carl J. Kozlosky et al. · Nature · 1997 · 3.1K citations

, , +14

Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis

Peter E. Lipsky, Désirée van der Heijde, E. William St. Clair et al. · New England Journal of Medicine · 2000 · 3K citations · Full text

, , +14

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

Larry W. Moreland, Scott W. Baumgartner, Michael Schiff et al. · New England Journal of Medicine · 1997 · 1.6K citations · Full text

, , +17

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

Marcia L. Moss, S.-L. Catherine Jin, Marcos E. Milla et al. · Nature · 1997 · 1.6K citations

, , +11

Human tumor necrosis factor. Production, purification, and characterization.

Bharat B. Aggarwal, William J. Kohr, P E Hass et al. · Journal of Biological Chemistry · 1985 · 919 citations · Full text

, , +13