Targeted minicircle DNA delivery using folate–poly(ethylene glycol)–polyethylenimine as non-viral carrier

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

‘Stealth’ corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption

Ruxandra Gref, Martín Luck, P. Quellec et al. · Colloids and Surfaces B Biointerfaces · 2000 · 1.7K citations

Natural Sciences, Materials Engineering, Materials Science +17

PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

Manfred Ogris, Silvia Brunner, Susanne Schüller et al. · Gene Therapy · 1999 · 1.2K citations

Pharmacy, Bioengineering, Pharmaceutics +16

Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes

N.D. Sonawane, Francis C. Szoka, A.S. Verkman · Journal of Biological Chemistry · 2003 · 1.1K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +14

Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.

Steven Weitman, Richard H. Lark, Leslie R. Coney et al. · PubMed · 1992 · 1K citations

Medicine, Cancer Biology, Oncology +8