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Amelioration of SLE-like manifestations in (NZBxNZW)F1 mice following treatment with a peptide based on the complementarity determining region 1 of an autoantibody is associated with a down-regulation of apoptosis and of the pro-apoptotic factor JNK kinase

Knockout MouseSignal TransductionAutoimmune DiseaseSle-like ManifestationsSignaling PathwayAutoantibody ProductionReceptor Tyrosine KinaseApoptosisAutophagyImmunologyCell DeathRegion 1AutoimmunityF1 MiceMedicineCell Biology