Neuroglobin, a Novel Intracellular Hexa-Coordinated Globin, Functions as a Tumor Suppressor in Hepatocellular Carcinoma via Raf/MAPK/Erk

A vertebrate globin expressed in the brain

Thorsten Burmester, Bettina Weich, Sigrid Reinhardt et al. · Nature · 2000 · 1K citations

Molecular Neuroscience, Vertebrate Globin, Neuroanatomy +7

Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

Toshiharu Sakurai, Guobin He, Atsushi Matsuzawa et al. · Cancer Cell · 2008 · 482 citations · Full text

Inflammation, Hepatology, Liver Tumorigenesis +12

Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury

Yunjuan Sun, Kunlin Jin, Xiao Mao et al. · Proceedings of the National Academy of Sciences · 2001 · 442 citations · Full text

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

Alastair J. King, Huaiyu Sun, Bruce Diaz et al. · Nature · 1998 · 430 citations

Signal Transduction, Signaling Pathway, Cell Regulation +8

Human Neuroglobin Functions as a Redox-regulated Nitrite Reductase

Mauro Tiso, Jesús Tejero, Swati Basu et al. · Journal of Biological Chemistry · 2011 · 280 citations · Full text