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Activation Pattern of Signal Transducers and Activators of Transcription (STAT) Factors in Inflammatory Bowel Diseases

DOI

229

Citations

31

References

2005

Year

Jonas Mudter, Benno Weigmann, Brigitte Bartsch, Dennis Strand, Peter R. Galle, Hans A. Lehr, Jan Schmidt, Markus F. Neurath
The American Journal of Gastroenterology

Abstract

The analysis of STAT activation patterns could serve as a helpful tool to characterize intestinal inflammation. Furthermore, the IL-6/STAT-3 rather than the IFN-gamma/STAT-1 signaling pathway emerges as a key target for the development of future therapeutic concepts in IBD.

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