Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.3K citations

Natural Sciences, Rna Splicing, Rna Biology +9

Hereditary Early-Onset Parkinson's Disease Caused by Mutations in <i>PINK1</i>

Enza Maria Valente, Patrick M. Abou‐Sleiman, Viviana Caputo et al. · Science · 2004 · 3.4K citations · Full text

Neurodegenerative Diseases, Mitophagy, Mitochondrial Function +14

PINK1 Protects against Oxidative Stress by Phosphorylating Mitochondrial Chaperone TRAP1

Julia W. Pridgeon, James A. Olzmann, Lih‐Shen Chin et al. · PLoS Biology · 2007 · 590 citations · Full text

Mitophagy, Signal Transduction, Mitochondrial Function +14

Impaired dopamine release and synaptic plasticity in the striatum of <i>PINK1</i> -deficient mice

Tohru Kitada, Antonio Pisani, Douglas R. Porter et al. · Proceedings of the National Academy of Sciences · 2007 · 534 citations · Full text

Synaptic Transmission, Neurotransmitter, Synaptic Signaling +19

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism

Laura Silvestri, Viviana Caputo, Emanuele Bellacchio et al. · Human Molecular Genetics · 2005 · 443 citations · Full text

Mitophagy, Pink1 Mutants, Genetics +19