Concepedia

Platelets Contribute to the Pathogenesis of Experimental Autoimmune Encephalomyelitis

Harald F. Langer, Eun Young Choi, Hong Zhou, Rebecca Schleicher, Kyoung‐Jin Chung, Zhongshu Tang, Kerstin Göbel, Khalil Bdeir, Antonios Chatzigeorgiou, Connie H. Y. Wong,

Circulation Research · 2012 · 201 citations · 49 references

DOIFull text

Open access

Abstract

Platelets contribute to the pathogenesis of EAE by promoting CNS inflammation. Targeting platelets may therefore represent an important new therapeutic approach for MS treatment.

References

49

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

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Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

Stephen Clark, C. Adrienne, Samantha A. Tavener et al. · Nature Medicine · 2007 · 2.2K citations

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Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

Christopher Lock, G Hermans, Rosetta Pedotti et al. · Nature Medicine · 2002 · 1.7K citations

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Platelets in inflammation and atherogenesis

Meinrad Gawaz · Journal of Clinical Investigation · 2005 · 1.4K citations · Full text

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Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor

Brian Savage, Enrique Saldı́var, Zaverio M. Ruggeri · Cell · 1996 · 1.2K citations · Full text

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