Concepedia

Transport Characteristics of Tramadol in the Blood–Brain Barrier

Atsushi Kitamura, Kei Higuchi, Takashi Okura, Yoshiharu Deguchi

Journal of Pharmaceutical Sciences · 2014 · 75 citations · 21 references

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References

21

Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line

Babette Weksler, Eva-Anne Subileau, Nicolas Perrière et al. · The FASEB Journal · 2005 · 1.3K citations

, , +12

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

Robert B. Raffa, Elmar Friderichs, Wolfgang Reimann et al. · Journal of Pharmacology and Experimental Therapeutics · 1992 · 1.2K citations

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Intracellular pH transients in squid giant axons caused by CO2, NH3, and metabolic inhibitors.

Walter F. Boron, Paul De Weer · The Journal of General Physiology · 1976 · 930 citations · Full text

, , +12

Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels

Ramzi Shawahna, Yasuo Uchida, Xavier Declèves et al. · Molecular Pharmaceutics · 2011 · 366 citations

, , +10

Affinity, potency and efficacy of tramadol and its metabolites at the cloned human µ-opioid receptor

Clemens Gillen, Michael Haurand, Dieter Johannes Kobelt et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2000 · 289 citations

, , +12