Inhibition of STAT3 signaling as critical molecular event in resveratrol-suppressed ovarian cancer cells

Abstract

Our results suggest the significance of STAT3 activation in the maintenance and survival of ovarian cancer cells. The activated STAT3 signaling is the critical molecular target of resveratrol. Resveratrol would be a promising candidate in the management of ovarian cancers, especially the ones with resistance to conventional therapeutic agents.