Synthesis and antiproliferative activity of triazenoindazoles and triazenopyrazoles: a comparative study

Rapid chromatographic technique for preparative separations with moderate resolution

W. Clark Still, Michaël Kahn, Abhijit Mitra · The Journal of Organic Chemistry · 1978 · 5.8K citations

Pharmacy, Chemistry, Analytical Chemistry +8

Antitumor Imidazotetrazines. 32.1 Synthesis of Novel Imidazotetrazinones and Related Bicyclic Heterocycles To Probe the Mode of Action of the Antitumor Drug Temozolomide

A. S. Clark, Bryan Deans, M. F. G. Stevens et al. · Journal of Medicinal Chemistry · 1995 · 120 citations

Medicine, Medicinal Chemistry, Pharmacology +8

In vitro and in vivo methazolastone-induced DNA damage and repair in L-1210 leukemia sensitive and resistant to chloroethylnitrosoureas.

Carlo V. Catapano, Massimo Broggini, Eugenio Erba et al. · PubMed · 1987 · 74 citations

Medicine, Molecular Biology, Pharmacology +13

Methylation of nucleic acids and urinary excretion of 14C-labeled 7-methylguanine by rats and man after administration of 4(5)-(3,3-Dimethyl-1-triazeno)-imidazole 5(4)-carboxomide

Joseph L. Skibba, George T. Bryan · Toxicology and Applied Pharmacology · 1971 · 62 citations

Medicine, Molecular Biology, Pharmacology +14

Elevated urinary excretion of 4-aminoimidazole-5-carboxamide in patients after intravenous injection of 4-(3, 3-dimethyl-1-triazeno) imidazole-5-carboxamide

Glenn E. Housholder, Ti Li Loo · Life Sciences · 1969 · 53 citations

Pharmacy, Pharmacokinetics, Pharmacology +10