Bryan Deans

Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice

Bryan Deans · The EMBO Journal · 2000 · 247 citations · Full text

Knockout Mouse, Embryonic Neurogenesis, Molecular Neuroscience +8

Antitumor Imidazotetrazines. 32.1 Synthesis of Novel Imidazotetrazinones and Related Bicyclic Heterocycles To Probe the Mode of Action of the Antitumor Drug Temozolomide

A. S. Clark, Bryan Deans, M. F. G. Stevens et al. · Journal of Medicinal Chemistry · 1995 · 120 citations

Alkylpurine–DNA–<i>N</i>-Glycosylase Knockout Mice Show Increased Susceptibility to Induction of Mutations by Methyl Methanesulfonate

Rhoderick H. Elder, Jacob G. Jansen, Robert J. Weeks et al. · Molecular and Cellular Biology · 1998 · 113 citations

Null Mice, Epigenetic Change, Genetics +16

Homologous recombination deficiency leads to profound genetic instability in cells derived from Xrcc2-knockout mice.

Bryan Deans, C.S. Griffin, Paul O’Regan et al. · PubMed · 2003 · 98 citations

Genetic Instability, Homologous Recombination Deficiency, Dna Damage +20

Expression levels of the DNA repair enzyme HAP1 do not correlate with the radiosensitivities of human or HAP1-transfected rat cell lines

C J Herring, Bryan Deans, Rhoderick H. Elder et al. · British Journal of Cancer · 1999 · 32 citations · Full text